This article traces the history and evolution of the Surviving Sepsis Campaign as a public health initiative through its several stages of development. The literature that has characterized clinical experiences with interventions related to the campaign is reviewed and conclusions discussed.
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.
Content published before 2002 is available via pay-per-view purchase only.
Subscribe:Subscribe to Clinics in Chest Medicine
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
- (Available at:)Accessed May 13, 2008)
- The 100,000 lives campaign: setting a goal and a deadline for improving health care quality.JAMA. 2006; 295: 324-327
- Surviving sepsis campaign guidelines for management of severe sepsis and septic shock.Crit Care Med. 2004; 32: 858-873
- Surviving sepsis campaign guidelines for management of severe sepsis and septic shock.Intensive Care Med. 2004; 30: 536-555
- Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2008.Crit Care Med. 2008; 36 ([erratum in: Crit Care Med. 2008 Apr; 36(4):1394–6]): 296-327
- Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock.Intensive Care Med. 2008; 34: 17-60
- Surviving sepsis—practice guidelines, marketing campaigns, and Eli Lilly.N Engl J Med. 2006; 355: 1640-1642
- Grading quality of evidence and strength of recommendations.BMJ. 2004; 328: 1490-1498
- Grading strength of recommendations and quality of evidence in clinical guidelines: report from an American College of Chest Physicians task force.Chest. 2006; 129: 174-181
- On behalf of the ATS Documents Development and Implementation Committee: an official ATS statement. Grading the quality of evidence and strength of recommendations in ATS guidelines and recommendations.Am J Respir Crit Care Med. 2006; 174: 605-614
- Duration of hypotension prior to initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock.Crit Care Med. 2006; 34: 1589-1596
- Early goal-directed therapy in the treatment of severe sepsis and septic shock.N Engl J Med. 2001; 345: 1368-1377
- Hemodynamic variables related to outcome in septic shock.Intensive Care Med. 2005; 31: 1066-1071
- Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock.JAMA. 2002; 288: 862-871
- Hydrocortisone therapy for patients with septic shock.N Engl J Med. 2008; 358: 111-124
- Intensive insulin therapy in critically ill patients.N Engl J Med. 2001; 345: 1359-1367
- Intensive insulin therapy in the medical ICU.N Engl J Med. 2006; 354: 449-461
- Intensive insulin therapy and pentastarch resuscitation in severe sepsis.N Engl J Med. 2008; 358: 125-139
- (Acute Respiratory Distress Syndrome Network. Available at:)Accessed June 15, 2008)
- The impact of compliance with 6-hour and 24-hour sepsis bundles on hospital mortality in patients with severe sepsis: a prospective observational study.Crit Care. 2005; 9: R764-R770
- A statewide implementation of surviving sepsis campaign bundles by the Colorado Critical Care Collaborative.Crit Care Med. 2006; 34 ([abstract supplement]): A99
- Implementation of an evidence-based standard operating procedure and outcome in septic shock.Crit Care Med. 2006; 34: 943-949
- Translating research to clinical practice: a 1-year experience with implementing early goal-directed therapy for septic shock in the emergency department.Chest. 2006; 129: 225-232
- Before–after study of a standardized hospital order set for the management of septic shock.Crit Care Med. 2006; 34: 2707-2713
- The association of sepsis syndrome and organ dysfunction with mortality in emergency department patients with suspected infection.Ann Emerg Med. 2006; 48 (590.e1): 583-590
- Implementation of a bundle of quality indicators for the early management of severe sepsis and septic shock is associated with decreased mortality.Crit Care Med. 2007; 35: 1105-1112
- Improvement in process of care and outcome after a multicenter severe sepsis educational program in Spain.JAMA. 2008; 299: 2294-2303
- Prospective external validation of the clinical effectiveness of an emergency department-based early goal-directed therapy protocol for severe sepsis and septic shock.Chest. 2007; 132: 425-432
- Economic implications of an evidence-based sepsis protocol: can we improve outcomes and lower costs?.Crit Care Med. 2007; 35: 1257-1262
Wade N. Thomas S. Kuhn. Revolutionary theorist of science. Science 1977;197(4299):143–5.
© 2008 Elsevier Inc. Published by Elsevier Inc. All rights reserved.