Responses and Limitations of the Respiratory System to Exercise
During maximal exercise, the gas exchange function of the lung is challenged because of the major cardiopulmonary changes that must occur to meet the increased metabolic demands imposed by exercise. In healthy untrained young adults, the respiratory system is able to meet these demands imposed on it during maximal exercise by implementing several key mechanisms. Nonetheless, there are several exceptional cases in which the lung is unable to accommodate the demands of exercise because of vascular or airway limitations.
aThe John Rankin Laboratory of Pulmonary Medicine, Department of Population Health Sciences, University of Wisconsin at Madison, Madison, WI, USA
bVermont Lung Center, University of Vermont, Burlington, VT, USA
cDepartment of Pediatrics, Critical Care Medicine, and Biomedical Engineering, University of Wisconsin School of Medicine, Madison, WI, USA
Corresponding author. The John Rankin Laboratory of Pulmonary Medicine, Department of Population Health Sciences, University of Wisconsin School of Medicine, Rm 4245 MSC, 1300 University Avenue, Madison, WI 53706-1532
This article was supported by National Institutes of Health grants HL15469-33 and T32 HL 07654-16.
ABSTRACT