Clinics in Chest Medicine
Volume 30, Issue 1 , Pages 1-16, March 2009

Approach to the Patient with Sepsis

  • Jason B. Martin, MD

      Affiliations

    • Division of Allergy, Pulmonary & Critical Care, Vanderbilt University Medical Center, 1161 21st Avenue South, Suite T-1210 MCN, Nashville, TN 37232-2650, USA
    • ,
  • Arthur P. Wheeler, MD

      Affiliations

    • Division of Allergy, Pulmonary & Critical Care, Vanderbilt University Medical Center, 1161 21st Avenue South, Suite T-1210 MCN, Nashville, TN 37232-2650, USA
    • Medical Intensive Care Unit, Vanderbilt University Medical Center, 1161 21st Avenue South, Suite T-1210 MCN, Nashville, TN 37232-2650, USA
    • Corresponding Author InformationCorresponding author. Division of Allergy, Pulmonary & Critical Care, Vanderbilt University Medical Center, 1161 21st Avenue South, Suite T-1210 MCN, Nashville, TN 37232-2650.

This article reviews the current understanding of sepsis, severe sepsis, and septic shock. The article details definitions and epidemiology pertinent to the sepsis syndrome. A brief discussion of mechanisms of disease is followed a description of organ-specific failures related to sepsis. A concise review of the latest treatment options for each organ dysfunction is provided.

Keywords: Sepsis, Septic shock, Definitions, Management

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PII: S0272-5231(08)00093-2

doi:10.1016/j.ccm.2008.09.005

Clinics in Chest Medicine
Volume 30, Issue 1 , Pages 1-16, March 2009

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